Louisville stunk it up (vs. their ranking) out-of-conference last year, too, (Western Kentucky and Minnesota on a neutral floors & UNLV at home), screwing the Big East before conference play, so I'm not surprised, though I am disappointed.
Marquette losing to NC St. at home after being up 14 also hurt, as did Providence losing to URI after holding a 16-point lead early in the 2nd half (this one was away and URI is not a pushover this year, though). With DePaul having the expected (especially with Koshwal out) loss at Vandy and St. John's having the expected loss at Duke, these three others hurt. The conference is now second in the Sagarin ratings (having held a fair lead just before), third in Pomeroy (having been a very close second) and a much less convincing first in the RPI (having been first by a wide margin before).
The remaining out-of-conference games for the Big East include:
Today Villanova essentially @ UMD at the Verizon Center
12/8 GU vs Butler at MSG
12/9 Providence @ GW (not a gimme, based on how the two teams are playing)
12/9 UConn vs Kentucky at MSG
12/9 St. John's hosting Georgia
12/10 Syracuse essentially @ Florida in St. Pete
12/10 DePaul vs Mississippi State in St. Pete (note: Koshwal will still be out)
12/12 GU vs Washington in Anaheim
12/12 Marquette @ Wisconsin
12/13 Villanova @ Temple (can't ever count out a decent Big Five team at home)
12/13 Cincy @ Xavier
12/16 Cincy @ UAB
12/19 Seton Hall hosting Temple
12/19 Notre Dame hosting UCLA (UCLA is down, but is from a power conference, and we should never underestimate the Irish's ability to play down to their opponent)
12/23 WVU hosting Mississippi
12/28 Rutgers @ UNC
1/1 WVU @ Purdue
1/2 Louisville @ Kentucky
1/2 Seton Hall vs VA Tech in Cancun
1/6 Syracuse hosting Memphis
1/17 Uconn @ Michigan
1/23 WVU hosting Ohio St.
1/30 GU hosting Duke
In some of these 23 games, Big East teams will be favored by a bit; in some they will be underdogs. Hopefully, there will be several more wins than losses. Losses in any of the other games on the schedule would be significant disappointments.
On a side note, our soft schedule thus far (Temple excepted, to whatever degree) has begun to hit our rating. Right now, our strength of schedule is at 335 in Sagarin (which is now "connected" and based only on games from this season), 331 in Pomeroy and 204 in the RPI; we're rated 24th, 38th and 47th, respectively. Wins in the upcoming week against Butler (now ranked below us with their losses to Minnesota & Clemson in the 76 Classic in Anaheim) and Washington (who could drop below us in the next poll with their loss @ Texas Tech) would go a long way to justify our currently-high rankings in the polls.